ABSTRACT
Background: Cervical precancerous lesions are disorders that can induce discoloration changes. Their detection is difficult in remote areas in the absence of adequate equipment. The objectives were to evaluate Smartphone performance in diagnosing cervical precancerous lesions in Tchibanga, Gabon. Methods: It was an interventional cross-sectional study to evaluate the validity and reliability of the smartphone as a tool for diagnosing atypical changes in the cervix. Study period was between July 1, 2017, to February 28, 2018, at the Tchibanga Regional Hospital (CHRT) and the University Hospital (CHU). The variability between examiners was determined according to Cohen's Kappa formula. The Gold standard test was the cytology. Results: Compared to the examiner -1, the examiner - 2 found a high percentage of inflammations as atypical transformations: 15.3% versus 9%. With regard to smartphonic impressions, the examiner-1 found the normal impressions almost equal to that of the examiner-2, 72.9% versus 72.2%. The concordance between positive smartphonic impressions was 93.8% and 95.5% between negative smartphonic impressions, with k = 0.86. Conclusion: In view of the above, the concordance between positive and negative smart phonic impressions was 93.8 and 95.5% with k = 0.86. The performance parameters being good, there is a need to use the smartphone as a tool for the diagnosis of precancerous lesions
Subject(s)
Precancerous Conditions , Uterine Cervical Neoplasms , Diagnosis , Smartphone , Uterine Cervical DiseasesABSTRACT
BACKGROUND: The aim of this study was to assess the usefulness of the beta subunit of hCG in cervicovaginal secretions as a biochemical predictor of spontaneous preterm delivery among pregnant women with and without preterm delivery risk.DESIGN: This was an eight-month prospective case control study of pregnant women with or without risk factors for preterm delivery. SETTING: Ifako- Ijaye General Hospital Lagos/ Lagos State University Teaching Hospital, Ikeja Lagos Nigeria. PARTICIPANTS: 150 pregnant women which consisted of 50 cases with preterm delivery risk and 100 controls without preterm delivery risk. INTERVENTIONS: A structured interviewer administered questionnaire which had been pretested, was used to collect data. Two cervicovaginal fluid samples at 26 weeks and 32 weeks were collected from each of the participants and it was quantitatively assayed using ELISA for presence of beta hCG. The participants were followed up till delivery. RESULTS: 15 participants out of the 50 cases delivered their babies preterm, while only 2 participants out of the 100 controls had preterm delivery. The 15 cases who delivered preterm had significant increase in their mean beta HCG value from 7.44±1.74 at 26 weeks to 32.6±1.32 at 32 weeks with p value<0.001. There was however no statistical difference in the mean beta HCG at 26 weeks and at 32 weeks for the control group. CONCLUSION: The concentration of beta HCG in the cervicovaginal fluid is a useful early predictor of preterm delivery especially among patients with risk factors.
Subject(s)
Uterine Cervical Diseases , Premature Birth , Fluids and Secretions , Chorionic Gonadotropin , Pregnant WomenABSTRACT
Notre travail a porte sur l'etude de 1455 cancers du tractus genital de la femme histologiquement diagnostiques de 1984 a 1993 dans les laboratoires d'anatomie pathologique des CHU de Cocody et Treichville. II ressort de notre etude que : les cancers du tractus genital feminin representaient 20;13 pour cent de l'ensemble des cancers et 40;27 pour cent des cancers de la femme ; la localisation cervicale etait nettement la plus frequente avec 70;45 pour cent et un age moyen de 35;28 ans ; une nette predominance des tumeurs d'origine epitheliales avec 84;81 pour cent en particulier le carcinome epidermoide (78;04 pour cent) ; les sarcomes et les autres types histologiques representaient respectivement 2;34 pour cent et 12;85 pour cent